Anejaculation means no semen is released during orgasm.
Retrograde ejaculation means semen goes backward into the bladder instead of exiting through the urethra.
In both cases, sperm may still be produced normally in the testes — but they need to be retrieved differently for conception.
These conditions affect delivery, not production.
That means many men with anejaculation or retrograde ejaculation can still father biological children using targeted medical or assisted reproductive options.
This article explains where these conditions fit, what changes in your fertility plan, and how early choices affect later results like sperm retrieval success and embryo quality.
Who It Helps
Testing and treatment for anejaculation or retrograde ejaculation are especially useful for men who have:
- Diabetes or nerve-related conditions affecting ejaculation
- Spinal cord injury or pelvic surgery (especially prostate or bladder surgery)
- Retrograde ejaculation suspected due to dry orgasm but sperm seen in post-ejaculatory urine
- Normal hormone and sperm production, but no semen after orgasm
- Failed semen collection before IUI or IVF cycles
When these signs appear, early testing helps clarify whether sperm are being produced normally — and how best to retrieve them.
Step-by-Step: Diagnostic & Treatment Sequence
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Initial Evaluation:
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Medical and sexual history, physical exam
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Hormone profile (FSH, LH, testosterone, prolactin)
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Post-ejaculatory urine test for sperm (key step in retrograde cases)
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Differentiate Type:
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Anejaculation: No semen release at all
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Retrograde: Semen seen in urine after orgasm
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Define Cause:
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Nerve injury, diabetes, surgery, medication, or psychogenic causes
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Treatment Pathway:
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Retrograde Ejaculation:
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Alpha-agonist medications (pseudoephedrine, imipramine) to restore forward flow
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If not effective, urine sperm retrieval for IUI or IVF/ICSI
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Anejaculation:
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Vibratory stimulation or electroejaculation (EEJ) for sperm collection
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If no response, surgical sperm retrieval (PESA, TESA, micro-TESE)
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Timing Checkpoints:
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Test early in the fertility pathway — before IVF cycle planning
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Coordinate sperm retrieval with egg collection to protect embryo quality and reduce stress
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Pros & Cons
Pros:
- Most cases allow biological paternity with proper technique
- Stepwise methods — start non-invasive, move to retrieval if needed
- Integration with IVF/ICSI possible for predictable outcomes
Cons:
- May require multiple attempts for adequate sperm retrieval
- Some procedures need anesthesia or coordination with IVF cycle timing
- Cost varies depending on technique and setting
Expectations:
With proper planning, sperm retrieval success rates are high, and IVF outcomes are comparable to conventional sperm use.
Costs & Logistics
| Procedure / Test | Typical Cost (INR) | Notes |
|---|---|---|
| Post-ejaculatory urine test | ₹1,000–₹2,000 | Simple outpatient test |
| Vibratory stimulation (PVS) | ₹5,000–₹10,000 | Non-invasive, often done in clinic |
| Electroejaculation (EEJ) | ₹25,000–₹40,000 | Usually under mild sedation |
| Surgical sperm retrieval (PESA/TESA/micro-TESE) | ₹50,000–₹1,00,000 | Coordinated with IVF/ICSI |
| IVF/ICSI cycle | ₹1.5–₹3.5 lakh | Add-on medications separate |
Insurance: Some plans cover diagnostic testing but not retrieval or IVF; request prior authorization and keep a simple cost tracker to prevent surprise bills.
What Improves Outcomes
- Tight glucose and blood pressure control in diabetics
- Review and, if possible, adjust medications that impair ejaculation (e.g., alpha blockers)
- Hydration and bladder alkalinization before urine sperm retrieval to protect sperm
- Psychological support and communication between partners to reduce stress
- Team coordination between urologist and embryologist to synchronize timing
Actions that rarely change outcomes: repeated home collection attempts without medical guidance, or delaying diagnosis beyond the IVF planning stage.
Case Study: From Uncertainty to Clarity
A 34-year-old man with diabetes reported “dry orgasm.”
Testing confirmed retrograde ejaculation — sperm seen in post-ejaculatory urine.
Medication improved forward ejaculation only partially, so sperm were retrieved from the bladder, washed, and used in an ICSI cycle.
The couple conceived on the first attempt.
The key: early diagnosis, clear communication, and synchronized lab coordination.
Mistakes to Avoid
- Assuming absence of semen means no sperm production
- Skipping post-ejaculatory urine testing
- Attempting random treatments without identifying cause
- Poor timing between sperm retrieval and egg collection
- Not coordinating between andrology and IVF teams
- A checklist and pre-cycle plan help reduce both stress and cost.
FAQs
Q: Can sperm from urine or electroejaculation be used for IVF?
Ans : Yes — once processed, these sperm work effectively for ICSI.
Q: Is electroejaculation painful?
Ans :It’s done under anesthesia or sedation, and typically well-tolerated.
Q: Can medications fix the problem permanently?
Ans : Sometimes, if caused by reversible factors or nerve dysfunction.
Q: Is sperm quality affected in retrograde cases?
Ans : Often slightly reduced, but IVF/ICSI compensates effectively.
Q: How soon can we plan treatment after diagnosis?
Ans : Usually within weeks — depending on lab coordination and female partner’s cycle.
Next Steps
- Book a free 15-minute nurse consult
- Upload your lab and semen reports for review
- Get a personalized cost and timing breakdown for your case
With the right plan, men with anejaculation or retrograde ejaculation can achieve excellent fertility outcomes — moving from uncertainty to clear, actionable steps.
Related Links

Dr. Kulsoom Baloch
Dr. Kulsoom Baloch is a dedicated donor coordinator at Egg Donors, leveraging her extensive background in medicine and public health. She holds an MBBS from Ziauddin University, Pakistan, and an MPH from Hofstra University, New York. With three years of clinical experience at prominent hospitals in Karachi, Pakistan, Dr. Baloch has honed her skills in patient care and medical research.




