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Posted on September 24, 2025

By Rashmi Gulati

Genetic Testing (PGT) for Embryos

Preimplantation Genetic Testing (PGT) is an advanced tool in IVF that allows embryos to be screened for chromosomal abnormalities or specific genetic conditions before transfer. For many families, PGT can improve outcomes and provide peace of mind.

What Is PGT?

PGT involves taking a few cells from a developing embryo (usually at the blastocyst stage, Day 5 or 6) and analyzing them in a specialized genetics lab. The embryo is frozen while results are processed, and only healthy embryos are selected for transfer.

Types of PGT

  • PGT-A (Aneuploidy) : Screens for abnormal chromosome numbers, which can cause miscarriage or conditions like Down syndrome.
  • PGT-M (Monogenic) : Tests for single-gene disorders, such as cystic fibrosis or Tay-Sachs disease.
  • PGT-SR (Structural Rearrangements) : Detects chromosomal translocations or inversions.

Benefits of PGT

  • Increases chance of successful implantation
  • Reduces miscarriage risk
  • Identifies embryos free from specific genetic diseases
  • Allows single embryo transfer with confidence

Limitations of PGT

  • Adds cost ($4,000–$7,000 per cycle)
  • Requires embryo biopsy, though risk is minimal
  • Does not guarantee pregnancy or rule out all genetic conditions

Who Should Consider PGT?

PGT may be most beneficial for :

  • Women over age 35
  • Couples with recurrent miscarriages
  • Patients with multiple failed IVF cycles
  • Carriers of genetic conditions

Those using donor eggs or sperm with known risks

Patient Story

Mark and Sofia had three failed IVF cycles due to early miscarriages. Their doctor recommended PGT-A, which identified chromosomally normal embryos. Their next transfer was successful, and they welcomed a healthy baby girl. They shared: “PGT gave us answers and restored our hope.”

FAQs

Q : Does PGT harm the embryo?

Ans : The biopsy is very safe with modern techniques, and embryos continue to develop normally after thawing.

Q : Is PGT mandatory?

Ans : No, it’s optional. It is most useful in high-risk cases.

Q: Can PGT guarantee a healthy baby?

Ans : No test can guarantee this, but PGT reduces risks of miscarriage and certain conditions.

Conclusion

PGT is a powerful tool that can improve IVF success rates and reduce risks for certain patients. At Surrogacy4All, we work with families to determine whether PGT is the right choice based on age, history, and genetic factors.

Learn more at:

https://www.surrogacy4all.com/guaranteed-embryos/

Contact – info@surrogacy4all.com | Call – 1-212-661-7177

Rashmi Gulati

Rashmi Gulati, MD, provides innovative, individualized health care that nurtures mind, body, and spirit. Since 2004 she has been the medical director at Patients Medical, where she delivers comprehensive personalized health care, treating each patient as a respected, unique individual. Through their integrative health care center in the heart of Manhattan, Dr. Gulati and her colleagues have become premier care providers serving patients locally and throughout the world.