Endometrial Receptivity Testing – Does It Really Improve Success?

One of the biggest challenges in IVF is ensuring the embryo is transferred at the precise moment when the uterus is most receptive. Endometrial Receptivity Analysis (ERA) is a test designed to determine that ideal window. But does it actually improve success rates?

What Is Endometrial Receptivity Testing?

ERA is a biopsy-based test that evaluates gene expression in endometrial cells. It identifies the window of implantation (WOI), a short period when the endometrium is most receptive to embryo implantation.

How ERA Works

1. The endometrium is prepared with hormones, similar to an IVF cycle.
2. A small biopsy sample of uterine lining is collected.
3. The sample is analyzed for genetic markers that indicate receptivity.
4. Results suggest whether the uterus is pre-receptive, receptive, or post-receptive.

Potential Benefits of ERA

• Helps identify the best timing for embryo transfer.
• May improve outcomes in women with repeated implantation failure.
• Allows for personalized embryo transfer protocols.

Limitations of ERA

• Not recommended for all patients—most conceive without it.
• Adds cost ($800–$1,500) and requires an additional cycle for biopsy.
• Studies show mixed results; some report improved outcomes, others show no significant difference.

Who Might Benefit Most?

ERA may be most beneficial for :

• Women with repeated failed embryo transfers.
• Patients with unexplained infertility despite good-quality embryos.
• Couples seeking additional data before future transfers.

Patient Story

Laura, age 37, experienced three failed transfers with high-quality embryos. Her ERA revealed her implantation window was shifted by 24 hours. On her next personalized transfer, she conceived successfully. She shared: “The test finally gave us the missing piece of the puzzle.”

FAQs

Q : Is ERA painful?

Ans : The biopsy can cause mild discomfort, similar to menstrual cramps.

Q : Should all IVF patients do ERA?

Ans : No. It is generally reserved for those with repeated implantation failures.

Q : Does ERA guarantee pregnancy?

Ans : No test can guarantee success, but it may improve timing for certain patients.

Conclusion

Endometrial Receptivity Testing can provide valuable insight into the timing of embryo transfer, especially for patients with multiple failed cycles. While not necessary for everyone, it may help optimize outcomes for select individuals.

Learn more at:

https://www.surrogacy4all.com/guaranteed-embryos/

Contact – info@surrogacy4all.com | Call – 1-212-661-7177