Variants of Uncertain Significance — How to Think About Them
A variant of uncertain significance (VUS) is a genetic finding where the lab sees a change in the DNA, but science cannot yet classify it as: harmful (pathogenic) harmless (benign) It is the genetic equivalent of:“Something is here, but we don’t know if it matters.” Because VUS findings are common—especially in expanded carrier screening and […]
Case Studies — Getting to Freeze Before Day 10
Key Takeaways Freezing by Day 10 is entirely achievable with the right stimulation strategy. Ideal candidates include those with predictable ovarian response, PCOS, travel-limited cycles, or high AMH where follicles grow rapidly. Antagonist protocols, tailored dosing, and flexible triggers allow safe early retrieval without compromising egg maturity. “Freeze-before-10” is especially valuable for cross-border IVF, medical […]
Ovulation Calculator — Irregular Cycle Considerations
Key Takeaways Irregular cycles make predicted ovulation windows narrower and less precise—but still trackable. Ovulation calculators use average cycle lengths, but additional biomarkers improve accuracy. Methods like LH testing, cervical mucus tracking, and cycle pattern review help confirm ovulation. Surrogates and intended parents must consider cycle variability when planning timelines. Accurate ovulation prediction supports natural […]
Second Child Planning at 42+ — Banking Now
Key Takeaways Fertility declines sharply after 40 — banking eggs or embryos early gives more options for a second child. Age affects egg quality more than egg quantity; early banking improves success rates. Embryo banking allows multi-cycle planning and reduces stress later. For many at 42–45+, donor eggs and surrogacy become strong pathways — early […]
Prior Authorizations — How to Win Approvals
Prior Authorizations — How to Win Approvals means understanding the insurer’s decision-making process before treatment begins.In plain English, it helps you see: What procedures and medications require prior authorization Why insurers deny requests (and how to prevent it) How medical notes, diagnosis codes, and timing influence outcomes How IVF, donor cycles, or surrogacy interact with […]
Thyroid‑Supportive Nutrition — Iodine and Selenium
Key Takeaways The thyroid depends on two key minerals—iodine and selenium—to produce and convert thyroid hormones. Deficiencies can affect fertility, metabolism, energy, and menstrual regularity. Simple food-level changes often correct mild imbalances without medication. Not everyone needs supplements—testing and individualized care are essential. Anti-inflammatory and nutrient-dense diets support long-term thyroid resilience. The thyroid is small, […]
Cross‑Border Journeys — Managing Distance and Uncertainty
Key Takeaways Cross-border surrogacy introduces unique emotional, legal, and logistical uncertainties. Stable communication systems and transparent agency/clinic coordination are essential. Early planning around visas, stay duration, and newborn documentation prevents delays. Emotional distance can be reduced through structured updates, video calls, and support groups. Choosing the right team is the single biggest predictor of a […]
Emergency Scenarios — Travel Restrictions and Illness
This article explains emergency scenarios — travel restrictions and illness within the International Surrogacy & Cross-Border Care pathway. It focuses on the choices that actually change outcomes, budgets, and timelines—so you can move forward with confidence. What It Is Emergency Scenarios — Travel Restrictions and Illness in plain English: understanding how unexpected global, national, or […]
Donor Agreements — Eggs, Sperm, Embryos
A donor agreement is a legal contract that defines the rights, responsibilities, and future boundaries when someone provides genetic material—egg, sperm, or embryos—to help create a child. It lays out: Parentage: donor relinquishes parental rights; intended parents assume full legal parentage. Use of material: IVF, surrogacy, number of embryos, future cycles. Contact level: anonymous, open-ID, […]
Future Horizon: In‑Vitro Gametogenesis (IVG) — Dual Guide
Key Takeaways In-Vitro Gametogenesis (IVG) is an experimental fertility technology still in research stages. IVG aims to create eggs or sperm from stem cells. The technology could expand fertility options for infertility, cancer survivors, and same-sex couples. IVG is not clinically available yet and faces ethical and regulatory review. Gestational surrogacy would likely remain essential […]
