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Posted on September 23, 2025

By Rashmi Gulati

IVF Add-Ons – Do PGT-A, ERA, and Immune Testing Improve Success?

Introduction

IVF has advanced significantly, but many patients are offered ‘add-ons’—extra tests or treatments promising higher success rates. This blog explores the most common add-ons and whether they truly help.

PGT-A Testing

Preimplantation Genetic Testing for Aneuploidy screens embryos for chromosomal issues. It may help reduce miscarriage risk, but it is not always necessary for younger patients with good embryos.

ERA Testing

Endometrial Receptivity Analysis aims to find the ideal time for embryo transfer. Studies show mixed results, and it may be most useful for patients with repeated implantation failure.

Immune Testing & Treatments

Some clinics recommend immune-related testing and therapies. Evidence is limited, and not all approaches are supported by science. Patients should ask critical questions before proceeding.

What the Data Shows

Large-scale studies suggest that while some add-ons help specific patients, many do not improve live birth rates overall. Costs can add up quickly.

Conclusion

IVF add-ons may be valuable in certain situations but are not universally necessary. Surrogacy4All helps patients understand the evidence, avoid unnecessary costs, and focus on proven approaches.

Rashmi Gulati

Rashmi Gulati, MD, provides innovative, individualized health care that nurtures mind, body, and spirit. Since 2004 she has been the medical director at Patients Medical, where she delivers comprehensive personalized health care, treating each patient as a respected, unique individual. Through their integrative health care center in the heart of Manhattan, Dr. Gulati and her colleagues have become premier care providers serving patients locally and throughout the world.